The services of Professor Abdulla Sultanov (deceased), Corresponding Member of the Academy of Sciences of Uzbekistan, Honored Science and Technology Worker, Doctor of Chemical Sciences, and Professor Abdulla Sultanov (deceased) contributed greatly to the establishment of this department. A.S. Sultanov is the first head of the department. In 1964-1974, he worked as a director of the Central Asian Research Institute of Oil Refining (currently UzKFITI Institute named after A. Sultonov) while managing the department. In 1969, for the first time, 17 students received the degree of engineer-technologist in the field of study "Technology of basic organic and petrochemical synthesis".

Since April 1971, professor O.S. Safayev, an inventor who served in Uzbekistan, doctor of chemical sciences, was appointed as the head of the department. Since this year, associate professor A. Kadirov, associate professor H.K. Salimova, assistants J. Saydaliyev and O. G. Azimov have started working as teachers. Due to the development of the oil and gas processing industry in Uzbekistan, since 1985, the department has started training personnel in the field of education "Oil and gas processing technology". In 1986-1996, the department was headed by candidate of chemical sciences, associate professor A.Q. Kadirov. From 1996 to 1997, candidate of chemical sciences at the department, associate professor Sh.P. Nurullayev, from 1997 to 2011, candidate of chemical sciences, associate professor D.N. Ismatov, from 2011 to 2012, candidate of chemical sciences, associate professor E.U. Teshabayeva, from 2012 to 2017 - until May 2018, candidate of chemical sciences, associate professor O.E.Ziyadullayev, from 2017 to 2019, doctor of technical sciences, professor A.S.Ibadullayev, from 2019 to 2023, the department is headed by doctor of philosophy (PhD) in technical sciences, associate professor O.Y.Aripdjanov those who came From March 2023, Doctor of Philosophy (PhD) Ismailov Boburbek Makhmudjanovich has been the director. Currently, the department is training specialists for chemical, oil and gas processing industry enterprises of our Republic and leading research institutes.